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There were two sets of auditions for this edition. The first was held simultaneously with those of the third regular season from March to May 2009. As these auditions were held a year in advance, the age limit was lowered to 14-17, since they would be within the correct age limit of 15-18 once the edition starts. A second set of auditions was held in March 2010, this time with an advanced registration through SMS, the age limit for auditioning was 15-18. A total of around 50,000 auditioned, from which 16 were chosen to compete in the new Edition.
There are many reasons for the use of the word Clash in the title. Primarily, the use of the Two House concept last seen in Pinoy Big Brother: Double Up (the third regular season) is again being used.